Course Syllabus

Title: Advanced Pathophysiology

Code: NU621

Credit hours: 3

Prerequisites: NU 500 – Theoretical Foundations for Nursing and NU 560 – Research Methods and Evidence-Based Practice

Course Description:

The course examines scientific concepts of pathophysiology essential to

diagnostic reasoning and clinical management of common disease states. The

dilemma of cost and need for laboratory and radiographic evidence to support

diagnosis is examined.

Program: Graduate Nursing

Program Outcomes:

1. Integrate scientific evidence from nursing and biopsychosocial disciplines, genetics, public health, quality improvement, and organizational sciences when designing and implementing outcome measures in diverse settings and through the lifespan.

2. Demonstrate leadership skills that emphasize ethical and critical decision- making, fiscal responsibility, inter-professional relationships that promote safe, quality care within a systems framework.

3. Apply methods, tools, performance measures, and evidence-based standards when evaluating quality indicators within an organizational system.

4. Synthesize theories, models and research findings inherent to nursing practice, education, and management to guide an organization or healthcare system towards achieving successful outcomes.

5. Apply client/patient care technologies and informatics to coordinate and ensure safe quality care and promote effective communication among members of the interprofessional healthcare team.



6. Analyze ethical, legal and sociocultural factors to influence policy development and healthcare delivery systems that promote the health of individuals and populations.

7. Articulate a leadership role within interprofessional teams through effective communication, collaboration and consultation with other professionals to manage, coordinate care and provide safe, quality family- centered and population based care.

8. Incorporate organizational and culturally sensitive client and population centered concepts in the planning, delivery, management and evaluation of direct and indirect evidence-based health promotion care and services to specified individuals, families and populations.

9. Implement scholarly activities in selected individuals, populations, and systems.

FNP Program Outcomes:

1. Critical Thinking: Demonstrate critical thinking and holistic caring as an advanced practice nurse.

2. Scientific Literature Analysis: Analyze scientific literature for application to selected diagnosis and treatment plans.

3. Ethical Principles: Synthesize ethical principles into the management and evaluation of healthcare delivery concerns in culturally diverse care settings

4. Competencies: Articulate a personal philosophy and framework acknowledging professional and accrediting agency competencies relating to the role and scope of practice of the family nurse practitioner.

5. Role of FNP: Implement the role of the family nurse practitioner in selected clinical settings.

Course Learning Objectives:

1. Integrate nursing and related sciences into the delivery of advanced nursing

care to diverse populations.

2. Incorporate current and emerging genetic/genomic evidence in providing

advanced nursing care to individuals, families, and communities while

accounting for patient values and clinical judgment.

3. Compare normal anatomy and physiology to alterations in function and

regulation of body organs and systems in response to stressors.




Topics & Learning Activities

Unit Topics & Activities Learning Objective Supported

Points Possible

1 THE CARDIOVASCULAR AND LYMPHATIC SYSTEMS Topic(s): HTN, CHF, CAD, AOD, MI, Ischemia Reading: Chapter 32: Structure and Function of the Cardiovascular and Lymphatic Systems Chapter 33: Alterations of Cardiovascular Function Chapter 34: Alterations of Cardiovascular Function in Children Discussion: Myocardial Infarction Assignments & Assessments: Unit 1 Quiz

1, 2, 3,


40 60


2 THE PULMONARY SYSTEM Topic(s): Pulmonary injury, pulmonary diseases, ARDS, OPD, pneumonia, TB, pulmonary embolism, pulmonary HTN, Cor pulmonale, cancer Reading: Chapter 35: Structure and Function of the Pulmonary System Chapter 36: Alterations of Pulmonary Function Discussion: COPD Assignments & Assessments: Unit 2 Quiz

1, 2, 3

40 60

3 THE ENDOCRINE SYSTEM Topic(s): Thyroid Disorders, Diabetes Reading: Chapter 21: Mechanisms of Hormonal Regulation Chapter 22: Alterations of Hormonal Regulation Chapter 23: Obesity and Disorders of Nutrition Discussion: Hyperthyroidism Assignments & Assessments: Unit 3 Quiz Endocrine Case Study

1, 2, 3

40 60




4 THE DIGESTIVE SYSTEM Topic(s): Acute and chronic gastritis, duodenal, gastric, and stress ulcers, ulcerative colitis, Chron’s disease, hepatitis, IBS, appendicitis, over and under nutrition, liver dysfunction, cirrhosis, cholelithiasis with cholecystitis. Reading: Chapter 41: Structure and Function of the Digestive System Chapter 42: Alterations of Digestive Function