Macrocytic Anemia Case Study .
Irving Olson, a 75 year old male comes to see you today with complaints of fatigue. You order a CBC and determine that Irving has macrocytic anemia. You order further testing and diagnose Irving with vitamin B12 deficiency.
- What are non-pharmacologic treatment strategies for the management of vitamin B12 deficiency?
- What pharmacologic treatment is used first line for a patient with vitamin B12 deficiency (be sure to include, at a minimum, drug name, dose, route, frequency)? What other treatment options exist? Why did you choose your treatment option over other available options (if applicable)?
- When is it appropriate to use vitamin B12 (administered orally)?
- What is the mechanism of action of the pharmacologic agents discussed in #2? How does the mechanism of action correlate with the physiology/pathophysiology of vitamin B12 deficiency anemia?
- What are the most common adverse effects of the pharmacologic agents discussed in #2?
- What is the cost of the pharmacologic agents discussed in #2?
- Discuss pharmacokinetics and pharmacodynamics of the pharmacologic agent discussed in #2? (Be sure to include, at a minimum, onset, peak, duration, half-life, etc).