Role of genetics in Strep Throat Infection
Role of genetics in Strep Throat Infection
The patient was suffering from strep throat infection which is caused by the bacteria Streptococcus pyogenes. The bacteria are in the group A streptococcus and is contagious spread through coughing, sneezing, sharing foods, drinks and can easily be picked from door doorknob or other surfaces (Elboray et al., 2018). Young people are at higher risk of strep infection and during winter the bacteria spread so fast as people like staying close.
Role genetics in Strep Throat Infection
Genetics play an important role in the susceptibility of strep throat infection. Children who are a genetically poor immune response to group A strep bacteria are at higher risk of getting the infection. Children with a family history of a frequent streptococcus throat infection are at high risk of a streptococcus infection.
Why the symptoms described Occurred
The patient present with a swollen throat as streptococcus bacteria colonized his throat and caused the infection. As the immune response tried to fight the bacteria swelling of the throat occurred. The bacteria caused damage to throat tissues causing swollen and red spots. The presence of pus in the throat is an indication that white blood cells died while fighting bacterial infection. The patient’s cervical lymph nodes were swollen as the production of immune cells increased in the lymph nodes (McCance & Huether, 2019).
Physiologic Response and Cells Involved
The immune system increases body temperatures to create an unconducive environment for streptococcus bacteria to thrive. As the immune cells attack streptococcus bacteria, they may also attack healthy body tissues causing complications such as rheumatic fever and inflammation of kidneys (Justiz-Vaillant & Zito, 2019). The patient may develop body aches as the bacteria infect other parts of the body. Cells involved in streptococcus infections are the simple squamous of the throat. The white blood cells mainly neutrophils and lymphocytes help to fight streptococcus infection. Children with a family history of a strep throat infection are at high risk than those without a family history (Elboray et al., 2018). Males children have higher chances of getting streptococcus infection than females although all races are at equal risk.
References
Elboray, S. N., Little, P., Nehal, M., Marzouk, D., & Reda, M. (2018). Assessment of different clinical variables associated with group a streptococcal throat infection among children in primary care practice. Egypt J Commun Med, 36. https://ejcm.journals.ekb.eg/article_16335_48e8dfc4e4852dd9c7e7e1436ce43e9e.pdf
Justiz-Vaillant, A. A., & Zito, P. M. (2019). Immediate hypersensitivity reactions. In StatPearls. Treasure Island, FL: StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK513315/ Credit Line: Immediate Hypersensitivity Reactions – StatPearls – NCBI Bookshelf. (2019, June 18).
McCance, K. L. & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Mosby/Elsevier.
