Hypothyroidism

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Hypothyroidism Case Study – 

Ruth Olson, a 74 year old female has a past medical history for hypothyroidism diagnosed on November 2013.  She admits to taking “thyroid replacement” medication but does not recall the name of the medication today.

Questions:

  1. What are non-pharmacologic treatment strategies for the management of hypothyroidism?
  2. What pharmacologic treatment is used first line for a patient with hypothyroidism (not autoimmune induced) (be sure to include, at a minimum, drug name, dose, route, frequency)? What other treatment options exist? Why did you choose your treatment option over other available options (if applicable)?
  3. What is the mechanism of action of your selected pharmacologic agent? How does the mechanism of action correlate with the physiology/pathophysiology of hypothyroidism?
  4. What are the most common adverse effects of your selected medication?
  5. What is the cost of your selected treatment option?
  6. Discuss pharmacokinetics and pharmacodynamics of your selected pharmacologic agent (be sure to include, at a minimum, onset, peak, duration, half-life, etc).
  7. Discuss dosing considerations for pharmacologic treatment of hypothyroidism related to the geriatric population.