Disorders Of Fluid, Electrolyte, And Acid–Base Balance
Case Study, Chapter 8, Disorders of Fluid, Electrolyte, and Acid–Base Balance
Norris, T. (2019). Porth’s Pathophysiology: Concepts of Altered Health States. 10th Ed. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins. ISBN: 978-1-4963-7755-5
Amanda is an 18-year-old with anorexia nervosa. She was recently admitted to an eating disorders clinic with a BMI of 13.9, and although she was a voluntary patient, she was reluctant about the treatment. She was convinced that she was overweight because her clothes felt tight on her. She complained that even her hands and feet “were fat.” One of her nurses explained that a protein in her blood was low. The nurse further explained that, as difficult as it may be to believe, eating a normal healthy diet would make the “fat hands and feet” go away
1. What protein do you suspect the nurse was referring to? How would a deficiency in this protein contribute to edema?
2. What is the difference between the physiology of pitting and nonpitting edema?
3. Because of her weakened condition, Amanda was moved around the ward in a wheelchair when she was not on bed rest. How does this affect her edematous tissues?
Follow this example; Example;
Case Study, Chapter 4, Genetic Control of Cell Function and Inheritance Marsha and Clement are both carriers of sickle cell anemia, a disease that is autosomal recessive. Their first child, Amelia, does not have the disease. Marsha and Clement are planning another pregnancy, but they are concerned about their second child having the condition. Clement’s father died from complications of sickle cell disease shortly before Amelia was born
sickle cell anemia
1. What is the likelihood of Marsha and Clement having a baby with sickle cell anemia? What is the chance the baby will be a carrier of the disease, just like the parents?
The gene is recessive, so the parents will have a 25% chance of giving birth to a child with the disease. There is a 50% chance that the baby will be a carrier
2. Marsha suggested to the nurse at the local family planning clinic that if the baby were a boy, he might have a higher risk of developing the disease, just like his grandfather. How would you respond?
The disease is autosomal in nature, meaning the disease arises from an abnormality on chromosomes 1 to 22. These chromosomes are alike in both males and females.
2. When Amelia, who does not have sickle cell anemia, grows up and marries someone who does have the disease, how likely will her children have the disease?
If Amelia has children to a father with sickle cell disease, the children will be carriers only.
